Date: June 9, 2015 (Tuesday) Time: 12:45 p.m. to 1:45 p.m.
Venue: The Lounge, 7/F, The Prince Philip Dental Hospital
Presenter: Miss Cao Ying, PhD Candidate (12:45 p.m. to 1:15 p.m.)
Title: Biomimetic remineralisation of hydroxyapatite on human enamel and dentine
Abstract: As the outermost layer of teeth, enamel is susceptible to caries due to the products of bacteria metabolism; or can be lost by trauma or by non-carious tooth loss. As the enamel lesions progress into dentine, tooth hypersensitivity often develops when the exposed dentine is subjected to stimuli. Traditional treatments include replacing the defected tooth structure with dental restorative materials such as amalgam, composite resin, and ceramics. However, marginal leakage, hypersensitivity and secondary caries often happens at the interface. Therefore, there is a need for scientists to design an alternative strategy to repair the tooth lesions. Biomimetic mineralisation is concepts from biomineralisation trying to transfer biomineralisation principles to the regeneration of new biomaterials. This study aimed to remineralise the demineralised enamel and dentine using biomimetic mineralisation methods.
Presenter: Miss Ito Leticia, PhD Candidate (1:15 p.m. to 1:45 p.m.)
Title: Effects of silver diamine fluoride on dentine demineralization and in combined use with laser irradiation
Abstract: In the mouth, there is always a dynamic process of demineralisation and remineralisation of the exposed teeth. Caries develops when the balance tips to demineralisation; but it can be arrested when the lesion is overwhelmed by remineralisation. Results from clinical trials showed that silver diamine fluoride can arrest and reharden carious lesions. Investigation also showed that enamel and dentine are harder and less soluble after application of SDF. In vitro studies also found that SDF can prevent Actinomyces naeslundii and Streptococcus mutans biofilm formation and reduce further demineralization. Studies also suggest laser irradiation after topical sodium fluoride application increase fluoride uptake on dental hard tissues. Current literature however found no study reporting the effect of laser irradiation on dentine treated with SDF under bacteria challenge. Therefore, this study investigated the effects of SDF on dentine demineralization and in combined use with laser irradiation under cariogenic biofilm.