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Archive for December 27th, 2012

Dec 27 2012

Dental Research Seminar

Published by under Dentistry

Date: January 3, 2013 (Thursday)

Time: 12:45 p.m. to 1:30 p.m.

Venue: Lecture Theatre II, G/F, The Prince Philip Dental Hospital


Presenter: Dr. Khaing War War, MPhil Candidate


Title: Dental pulp stem cells isolation from Inflamed dental pulp tissues and comparisons of cytotoxic effcets of endodontic irrigants on dental pulp stem cells


Abstract: The dental pulp is regarded as most accessible source of mesenchymal stem cells that can be obtained at any age of an individual’s life. Many authors have been proposed that stem cells can be recruited from dental pulp tissues that are extirpated and discarded during invasive pulp treatments. Dental stem cells may be found from various sources situated inside or around the tooth. Inflamed pulp can be one such source and it has been demonstrated that functional putative stem cells exist in clinically inflamed pulps.


Regenerative approach for pulp canal therapy depends on the proliferation of seeded dental pulp stem cells within the root canal space that has been cleaned and disinfected by chemical irrigation agents. These chemicals may influence the attachment and survival of stem cells on the root canal dentine with direct impact on the regeneration of tissues. The aims of this in vitro study are to isolate stem cells from inflamed dental pulp tissues and to investigate the ability of stem cells to attach to root canal dentine that has been treated by various endodontic irrigants. This would be an indirect measure of the cyototoxic effects of these irrigants on the vitality of dental pulp stem cells.



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